The “NeuroStem Cell facility” at CHINTA is at the forefront of human stem cell research, focusing on hiPSC-derived neurons and astrocytes and their implications for neurodevelopmental and degenerative disorders such as FXS and SCAs.
At the centre of this endeavor lies the limitless capacity of stem cells to transform into various cell types, offering novel insights into human biology and its disease mechanisms. Specifically, we’re intrigued by the non-neural lineage, where hiPSCs give rise to neurons, astrocytes, oligodendrocytes, immune cells- the key players in brain function.
Our state-of-the-art lab adheres to international standards, featuring clean rooms, biosafety hoods, tri-gas incubators, brightfield microscopes, and centrifuges for culturing neuronal and glial stem cells. Equipped with cutting-edge technology, we screen novel compounds that can modulate neural stem cell behavior and function, aiming to develop groundbreaking treatments for disorders like autism, Alzheimer’s, and ataxia.