RISE of TCG CREST along with TCGLS is working on the development of some novel antiviral formulations for multiple uses based on the notion of disrupting the lipid bilayer self-assembly with co-functional additives for Interrogating and Neutralizing Viruses (including Corona) and Microbes on Contact. Such formulations are aimed at making the Hospital Assistive devices and PPEs more secure while the medical community and other professionals fights the pandemic on the war front. They could also be used on various surfaces to protect them over time.
As India is opening up for business and human activities, the Corona viral threat will keep on spreading even more. We are being constantly advised that the virus spreads very rapidly, primarily through human-to-human contact and interaction via aerosols bearing viral content. A symptomatic or even an asymptomatic person can pass on the virus by sneezing or engaging in a conversation from a close quarter whereby invisible (aerosol) droplets carrying the virus can inadvertently land on the other person and cause infection. The virus also has a finite residence time on different types of surfaces like metallic, wooden, plastics and the like, and therefore retains the potential to transmit infection. All of us will need to be equipped with strategies and novel tools/ideas to save ourselves against infections, which are quite likely to happen because of unintentional or inadvertent compromise with respect to social distancing – a key to limit the rapid spreading of the virus. This will be even more important for people fighting this challenge on the frontline such as the medical personnel, police personnel, vendors of essential supplies and the corresponding systems, and public spaces such as the hospitals, police stations, shops and malls. This calls for creative, yet simple and inexpensive solutions that are rapidly and easily implementable on a massive scale. The currently envisaged solution(s) being designed and developed by TCG CREST is an attempt in that direction. TCGLS is also contributing to the development of special molecular systems that could actively engage with the viral self-assembly.
Our research teams are involved in a variety of detailed studies involving chemistry of materials, thorough studies on the synthesis and characterizations of materials, and the formulations including their interactions and stability. The development team is preparing prototype formulations based on these new concepts and innovations. Certain basic characterization tests are being performed simultaneously in-house.
TCG CREST has collaborated with IISER, Pune to conduct the cyto-toxicity tests and Interactive Research School for Health Affairs(IRSHA), Bharati Vidyapeeth to conduct the Antiviral Assessment of antimicrobial coating against SARS –CoV2 virus
Led by renowned scientist Professor Satish Ogale, Director of Research Institute of Sustainable Energy (RISE) of TCG CREST and Dr. Soumen Sensarma, AVP, of TCGLS and his team Sandip Roy, Joydeb Manna and Newton Roy and research scientists Aishwarya Yadav and Kanchan Barve from IISER. Ayananshu Banerjee, Head Projects of TCG CREST is the project manager and Professor Sabyasachi Bhattacharya, Director of TCG CREST is the Project Director.